Dysregulation of strongyloidiasis: a new hypothesis.

A review of Disruptive Mood Dysregulation Disorder, a new disorder in the DSM-5

Disruptive mood dysregulation disorder (DMDD)  is a new disorder that has been added to the mood disorders category in the Fifth Diagnostic and Statistical Manual of Mental Disorders to distinguish chronic non-periodic irritability from periodic irritability of bipolar disorder. The main feature of DMDD is chronic and severe irritability. Since it is a new diagnostic entity, not much research h...

Metronomic Effect as A New Hypothesis in Maintenance Therapy of Acute Lymphoblastic Leukemia

solution of security constrained unit commitment problem by a new multi-objective optimization method

چکیده-پخش بار بهینه به عنوان یکی از ابزار زیر بنایی برای تحلیل سیستم های قدرت پیچیده ،برای مدت طولانی مورد بررسی قرار گرفته است.پخش بار بهینه توابع هدف یک سیستم قدرت از جمله تابع هزینه سوخت ،آلودگی ،تلفات را بهینه می کند،و هم زمان قیود سیستم قدرت را نیز برآورده می کند.در کلی ترین حالتopf یک مساله بهینه سازی غیر خطی ،غیر محدب،مقیاس بزرگ،و ایستا می باشد که می تواند شامل متغیرهای کنترلی پیوسته و گ...

Modeling the Calcium Dysregulation Hypothesis of Alzheimer's Disease

Several types of neural plasticity must be perfectly orchestrated for a proper functioning of biological neural networks. In this work we present a computer simulation of the Alzheimer's Disease, taking into account one of the most accepted models of Alzheimer's Disease: the calcium dysregulation hypothesis. According to Cudmore and Turrigiano calcium dysregulation alters the shifting dynamic o...

A new cancer hypothesis.

Despite intensive efforts to cure breast cancer, treatment generally fails, as evidenced by the age-adjusted mortality rate for breast cancer. For 60 years, breast cancer mortality remained virtually constant. As treatment failed to improve the life prospect of the average patient, it is based on false premises, e.g. Halsted's hypothesis, according to which the tumor is the only threat to the p...